Add a Review
- To add a review, simply search for your paper.
- DOI is best but the full title also usually works.
- When you find it, click on the Add a Review link as shown below.
Covalent attachment of small organometallic molecules to COOH-MWCNTs was successfully achieved using the described methods of EDC/NHS coupling. A qualitative yield was achieved which allowed for a unique route to create redox active MWCNTs. After exploration...
Summary:
An efficient method for the synthesis of diazoacetates from the coresponding bromoacetates and N,N'-ditosylhydrazine has been described. In fact, diazoacetates can be prepared from various alcohols by acylation with bromoacetyl bromide, followed by...
The manuscript entitled “Regioselective Synthesis of Substituted Rubrenes” is nicely written and excellent piece of work. Manuscript describes a method to generate Rubrene derivatives using a Diels Alder reaction and Phenyl lithium addition as key steps....
PNU-95666E (sumanirole) was reported to be a highly selective D2 receptor full agonist. It was originally developed for the treatment of Parkinson’s disease. An eight steps synthesis was developed for the scale up of enantiomerically pure (R)-sumanirole with...
Summary:
Synthesis of various silacycles has been reported.
The Reaction of Interest:
Synthesis of t-BuSiHCl2 (18.5%, 50 mmol) via reaction of HSiCl3 (2 equiv) with t-BuLi.
Practical Observations:
1. Synthesized compound 1 and another similar compound using the procedure described in this article.
2. Used 0.2 mmol Iridium instead of 0.1 mmol as reported. The reaction was monitored by TLC and after 48 hrs, all starting materials was consumed. The...
This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups,...
Summary:
A new series of bile acid-based trioxanes have been synthesized and assessed for their antimalarial activity against multidrug-resistant Plasmodium yoelii in Swiss mice by oral route.
The Reaction of Interest:
Decarboxylative oxidation of...
Summary:
This paper reports a CTAB-catalyzed method developed for the synthesis of 2-substituted benzothiazoles by the condensation of 2-aminothiophenol with aldehydes (RCHO: R = Alkyl, Aryl, Heteroaryl, 2-Arylformyl). Use of cetyltrimethyl ammonium...
Summary:
This paper describes the density functional theoretical study on oxorhenium(V) complexes incorporating quinoline or isoquinoline carboxylic acids. The study is aimed at understanding causes for the difference in stabilities of particular isomers...
Summary:
This paper reports the synthesis of a Schiff base ligand (L) by reaction of 5,5’-methylene-bis-salicylaldehyde with amidol (2,4-diaminophenol). The applicability of this ligand as a new fluorescent Cu(II) sensor in aqueous medium was assessed. A...
The article presents a synthetic methodology to prepare chiral N,N-disubstituted, 1,2-diamines, which can be convenient precursors to tridentate ligands.
Particularly, I used the synthetic route using cyclohexane-1,2-diamine (both racemic and enatiopure)...
Synthesized mesitylcopper by following the procedure.
(1) High quality anhydrous solvents (THF/dioxane/Toluene) and good argon or nitrogen protection for all the operations are key to get high yield and quality product, since the mesitylcoppor solution is...
Description of Study
Szostak and coworkers reported highly chemoselective reduction of amides ( primary, secondary, Tertiary) to alcohols using SmI2 /Amine /H2O under mild conditions. They reduced amide to alcohol by stirring amide (0.1mmol) with...
Spirobifluorene: Synthesized spirobifluorene following the reported procedure (page 324-325) using 2-iodobiphenyl as starting material. It was difficult to isolate nmr-clean product and the yield was low, although they reported very high yield. Instead of...
Review:
This article describes the structure optimization and initial mechanistic understanding of a simple thiourea catalyst for the enantioselective alkylation of indoles with nitroalkenes. The indole ring has proven to be a “privileged” structure in...
Synthesized compounds 1, 2 and 8. These reactions were successfully reproduced at large scales (up to 10 times).
Synthesized 4,4’-didodecyl-2,2’-bithiophene (2b), and a similar compound 4,4’-dihexyl-2,2’-bithiophene (dhexbTH) following the procedure for the synthesis of 2a and 2b (given in supporting info.).
The yield for the synthesis of pure 2b was 50 %, which is...
This paper describes the synthesis and characterization of a series of thiophene- and N-methylpyrrole-based low band gap polymers incorporating o-quinoid acceptors such as thienopyrazine, quinoxaline, benzothiadiazole, pyrazinoquinoxaline,...
This communication by Furstner and co-worker reported a novel rearrangement of methylenecyclopropanes 3 for the construction of variously substituted cyclobutenes and derivatives.
I am particularly interested in the preparation of cyclopropylidene bearing...