The experimental section was adequately detailed in procedure and results describing necessary DMA and MDSC data were given. No substantial differences were recorded while reproducing similar results.
This communication was outstanding in providing a comprehensive study of polyurea properties for:
1) Development of constitutive model for polyurea at high strain rate loading conditions
2) Study of polyurea behavior from a quasi-static to ultra high...
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This paper reports the chemosensing properties of a commercially available fluorescent probe, 1,8-diamino naphthalene for copper ion detection in the aqueous medium and its application in bioimaging. The proposed mechanism involves fluorescence...
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An efficient and green method for synthesis of 2 substituted benzimidazoles has been described. Despite previous methods being available in literature for synthesis of such compounds, the ease of operation, use of common and non-toxic solvent and...
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This paper reports an efficient method for synthesising benzimidazoles through cascade reactions of o-haloacetoanilide derivatives with amidine hydrochlorides. 10 mol % CuBr was used as the catalyst and Cs2CO3 as the base. The reactions were...
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This paper reports an efficient method for aldol condensation between a methyl 3-hydroxy-5-oxohexanoate derivative and a pyrimidine carbaldehyde comprising the core structure of rosuvastatin. The authors have described the method as an...
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A simple, convenient, and environment-friendly method for synthesis of 1,2-disubstituted benzimidazoles in high yields under extremely mild conditions, has been described. The methodology described, involves condensation of o-phenylenediamine...
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An easy, green, efficient and simple for synthesis of derivatives of benzimidazole-, benzothiazole- and benzoxazole-2-thiol has been described. Although previous methods are available in literature for synthesis of such compounds, this method...
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This paper reports an interesting property of the O, N and S donor ligand 2-(2’-Hydroxy-3’-methoxyphenyl)benzothiazole which makes it switch chelating donor sites from O, S (at pH < 5.0) to O, N (above pH 5.0) while reacting with Cu(II) acetate...
This paper does a thorough analysis of structure and property relationships. The analyiss is thorougouh and well backed up by data. I found the secion on deswollen materials particularly helpful and interesting.
Well written paper. The technique of using a removabile filler to direct pore size in a membrane is an innovative method and should be studied more.
The data in this paper is veryw ell laid out. The data is easily reproducable and the work is easy to follow.
Covalent attachment of small organometallic molecules to COOH-MWCNTs was successfully achieved using the described methods of EDC/NHS coupling. A qualitative yield was achieved which allowed for a unique route to create redox active MWCNTs. After exploration...
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An efficient method for the synthesis of diazoacetates from the coresponding bromoacetates and N,N'-ditosylhydrazine has been described. In fact, diazoacetates can be prepared from various alcohols by acylation with bromoacetyl bromide, followed by...
The manuscript entitled “Regioselective Synthesis of Substituted Rubrenes” is nicely written and excellent piece of work. Manuscript describes a method to generate Rubrene derivatives using a Diels Alder reaction and Phenyl lithium addition as key steps....
PNU-95666E (sumanirole) was reported to be a highly selective D2 receptor full agonist. It was originally developed for the treatment of Parkinson’s disease. An eight steps synthesis was developed for the scale up of enantiomerically pure (R)-sumanirole with...
Summary:
Synthesis of various silacycles has been reported.
The Reaction of Interest:
Synthesis of t-BuSiHCl2 (18.5%, 50 mmol) via reaction of HSiCl3 (2 equiv) with t-BuLi.
Practical Observations:
1. Synthesized compound 1 and another similar compound using the procedure described in this article.
2. Used 0.2 mmol Iridium instead of 0.1 mmol as reported. The reaction was monitored by TLC and after 48 hrs, all starting materials was consumed. The...
This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups,...