Summary:
This paper reports the synthesis of 2-arylbenzothiazoles via cyclocondensation of 2-aminothiophenol with various aldehydes. Polyethylene glycol-400 (PEG-400) has been used as both solvent and catalyst for the process. The procedure applied, is...
Summary:
The article presents the synthesis and characterization of two mononuclear Re(V) complexes. DFT and TD-DFT methods were employed for exploring the electronic structure and absorption spectra. Furthermore, the complexes were also tested for...
I used the published synthethic methods for both deoxy and methoxy derivatives with some modifications and obtained a lot higher yields.
Deoxy: 2 eq of 1,1′-Thiocarbonyldiimidazole is enough (paper is 2.5 eq) and I used 1,2-dichloroethane instead of CH2Cl2...
This paper by Verkade and co-workers describes a superbase P(MeNCH2CH2)3N mediated selective monoalkylation of active-methylene compounds. Although malonate alkylation has been known for many years, it is very difficult to obtain really good yields for...
Synthesized (20) using the similar (not exactly same) procedure (Scheme 2) as was written in the paper.
1,4-Diaminobutane was firstly protected by mesitly chloride in DCM (overnight under reflux condition). The protected intermediate was then...
The article is about versatile synthetic strategy for preparing enantiomerically pure (N)-methanocarba ring containing monophosphates as a potent agonist for P2 receptors.
I have successfully reproduced the synthesis of compound (2, MRS2339) from...
The procedure was adapted for the covalent attachment of an organometallic complex to chitosan backbone for use in a glucose oxidase bioanode. The procedure was done in both acidic (as in paper) and basic conditions (for comparison) for the following...
I need prepare a series of 2-amino-pyridines around 2003, and found this paper by SciFinder.
I tested the reaction of 1-Boc-piperidine and 2-chloro-3-methyl- pyridine in 50mg scale using 5 mmol% catalysts.
The reactions were not completed in 3h at rt....
Unseld et al reported a novel mono and bis (alkynyl) Mn(II) and Mn(III) complexes with terminal or trimetyltin substituted acetylenes. In particular I was interested on stanylation terminal hydrogen at ethynyl aryls. I used this approach to stanylate...
I adopted the synthesis reported in the paper for selective sulfation of compound 2 in the synthesis of 3’O Sulfo β-methyl D-galactoside similar in structure to compound 2 save for a methyl group at the anomeric position in place of an azidoethyl. I altered...
The coupling reaction between a carboxylic acid and an alcohol to generate an ester needs a carbodiimide coupling agent. in the reference, the authors report the use of EDCI to prepare compound 1. I have used the same procedure in the synthesis of 1 though...
Summary:
Deoxydehydration of glycols and epoxides catalysed by oxorhenium complexes is described in this paper. Methyl trioxorhenium (MTO) was the choice as the catalyst for the reactions. The use of other catalytic conditions for such reactions are...
Summary:
This paper reports 1-Naphthyl-2-cyanoacetamide used as a precursor for the synthesis of different novel heterocyclic moieties such as 5-Aminopyrazole, thiazolinone, pyrazolo[1,5-a]pyrimidine, 4H-pyrazolo[3,4-d]pyrimidin-4-one and pyrazolo[3,4-d...
Summary:
This paper describes the density functional theoretical study on oxorhenium(V) complexes incorporating quinoline or isoquinoline carboxylic acids. The study is aimed at understanding causes for the difference in stabilities of particular isomers...
Summary:
This paper reports an interesting property of the O, N and S donor ligand 2-(2’-Hydroxy-3’-methoxyphenyl)benzothiazole which makes it switch chelating donor sites from O, S (at pH < 5.0) to O, N (above pH 5.0) while reacting with Cu(II) acetate...