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Grindstone chemistry: protic ionic liquid-substrate tuned green synthesis of 1,2-disubstituted and 2-substituted benzimidazoles with outstanding selectivity


14 Dec 2016

Innovative, but better methods known

Summary:

An efficient and environmentally benign method for synthesis of 1,2-disubstituted and 2 substituted benzimidazoles has been described. Although previous methods are available in literature for synthesis of such compounds, the ease of operation,...

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Reusable fluorescent photocrosslinked polymeric sensor for determining lead ions in aqueous media


22 Dec 2016

Excellent method. Minor adjustment will make it even better

Summary:

A polymeric film as fluorescent sensor for detection of Pb2+ in aqueous solutions, synthesised from 1-vinylimidazole, poly(ethylene glycol) diacrylate and trimethylolpropane triacrylate has been described. The manuscript also describes the...

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Efficient Route for Cyclic Olefin Polymerization:  Nonchelated Monodentate Benzimidazole Nickel(II) Complex Catalysts for Vinyl Polymerization of Norbornene


24 Dec 2016

Innovative approach but low yields

Summary:

This article describes a method for cyclic olefin polymerization employing a non-chelated monodentate benzimidazole Ni(II) complex. The specific reaction catalysed, is the vinyl polymerization of norbornene. The article also describes the methods...

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A mild and efficient amide formation reaction mediated by P(OEt)3and iodine


24 Dec 2016

Reproducible reactions. Can be extended to other analouges

Summary:

This paper describes a novel method for efficient synthesis of amides through reaction of carboxylic acids with amines by activation with P(OEt)3 and Iodine. The novelty lies in easy amidation of several primary and secondary amines to synthesize...

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Synthesis, structure and study of azo-hydrazone tautomeric equilibrium of 1,3-dimethyl-5-(arylazo)-6-amino-uracil derivatives


24 Dec 2016

Lives up to the claims by the authors

Summary:

This paper reports the synthesis of hexamethylenebisacetamide (HMBA) without organic solvent or gas protection via amide exchange reaction of hexamethylenediamine (HDA) with CH3CN and H2O catalysed by CuO. The authors report the method to be more...

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1-Naphthyl-2-cyanoacetamide in heterocyclic synthesis: synthesis and evaluation of the antimicrobial activity of some new pyridine, pyrimidine, and naphtho[2,1-b]oxazine derivatives


01 Jan 2017

Very well reproducible but greener solvents need to be used

Summary:

This paper reports the reactivity of the methylene group of 1-naphthyl-2-cyanoacetamide 1 which was tested towards different reagents. These new compounds have been reported to be characterized by elemental analysis, IR, 1HNMR, 13C NMR, and mass...

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Thermochemistry of halogen-containing organic compounds with influence on atmospheric chemistry


31 Jan 2017

Good study - need to find methods for iodinated-molecules

Summary:

This research article reports a study on the thermocehemical behaviour of halogen-containing molecules in atmospheric chemical processes. The thermodynamic and thermochemical model of these components helps in understanding the interactions in...

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Selective Bromination of Perylene Diimides under Mild Conditions


09 Dec 2016

Good experimental, some modification to work-up

In this paper, selective bromination of perylene diimides is described. I was able to reproduce the bromination of 1a. However, the workup involves evaporating large volumes of bromine. I was able to isolate similar yields of products by quenching the...

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Three new mononuclear group 12 complexes with benzimidazole


15 Dec 2016

Reproducible but very routine work

Summary:

This paper describes the synthesis of three iso-structural Zn(II), Cd(II), and Hg(II) complexes with 1-benzyl-2-phenyl-1H-benzimidazole (BPB). Single crystal X-ray determination of CdBPB and HgBPB were done along with Structural analysis of ZnBPB...

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Selective quenching of benzimidazole derivatives by Cu2+ metal ion


01 Jan 2017

Many details omitted which makes it clumsy to repeat

Summary:

This paper reports the binding effect of some novel benzimidazole derivatives with Cu2+ metal ion by solution spectral studies. Benzimidazole complexes (16) were studied for fluorescence quenching by Cu2+ in comparison to Fe3+, Mg2+, Ag+, K+...

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Synthesis and in Vitro Anti-Tumor Activity of A New Class of Acyclic Thioglycosides


31 Jan 2017

Innovative approach - Lower yields

Summary:

This paper reports the synthesis of a new class of acrylamide thioglycoside derivatives utilizing a one-pot synthesis. Further heating of the resultant glycosides with hydrazine is reported to give pyrazole derivatives. Among those synthesized,...

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Isolation and reactions of .alpha.-lithio N,N-dimethylacetamide


09 Dec 2016

Reproducible Experimental

Summary: The paper discusses the synthesis, reactivity and stability of α-lithio N,N dimethylacetamide.

The paper described carefully the use of various solvents (pentane, THF) and their impact on the formation of the desired product.

It also described...

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A Convenient Synthesis of Novel Bifunctional Prochelators for Coupling to Bioactive Peptides for Radiometal Labelling


09 Dec 2016

Extremely helpful and reliable paper

 

Summary

The article describes the synthesis of cyclen based chelators which can accommodate and stabilize di-and trivalent metal ions for biomedical applications. The chelators were synthesized first by monoalkylating cyclen (1,4,7,10...

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DIPHENALDEHYDE


09 Dec 2016

Reliable Procedure

The procedure described in this paper is very reliable. The ozone should be used in a fully functional fume hood as described.

1. Synthesized 10.1 g of crude diphenaldehyde starting from 10.0 g of phenanthrene.

2. The crude 1H-NMR of product is 80%...

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Rapid determination of trace level copper in tea infusion samples by solid contact ion selective electrode


22 Dec 2016

Should include Mn & Al data for clarity

Summary:

A new copper selective solid-state electrode based on o-xylylenebis(N,N-diisobutyldithiocarbamate) ionophore has been described. It has been developed for selectively measuring the copper levels found in the tea infusion samples. Robust, cheap...

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Theoretical study of borazine and substituted borazines using density functional theory method


23 Dec 2016

Good theory. Experimental data can add value.

Summary:

This paper describes the theoretical study on borazine and substituted borazines by the means of density functional theory. Amino group was used as the common donor group while four acceptor groups namely –NO2, –C≡N, –COCl and –NMe2 were chosen...

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“On water” organic synthesis: a highly efficient and clean synthesis of 2-aryl/heteroaryl/styryl benzothiazoles and 2-alkyl/aryl alkyl benzothiazolines


01 Jan 2017

Excellent practical method. Highly recommended.

Summary:

A convenient, clean and environmentally benign method for ‘‘on water’’ synthesis of benzothiazoles/benzothiazolines has been described. Although previous methods are available in literature for synthesis of such compounds, the ease of operation,...

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Eco-friendly synthesis of 2-substituted benzothiazoles catalyzed by cetyltrimethyl ammonium bromide (CTAB) in water


18 Feb 2017

Innovative but has errors which affects reproducibility

Summary:

This paper reports a CTAB-catalyzed method developed for the synthesis of 2-substituted benzothiazoles by the condensation of 2-aminothiophenol with aldehydes (RCHO: R = Alkyl, Aryl, Heteroaryl, 2-Arylformyl). Use of cetyltrimethyl ammonium...

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Dynamic Properties of Polyurea


04 May 2017

Strain rate/ impact loading dependency of polyurea

This communication was outstanding in providing a comprehensive study of polyurea properties for: 

1) Development of constitutive model for polyurea at high strain rate loading conditions

2) Study of polyurea behavior from a quasi-static to ultra high...

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