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Markovnikov Alkyne Hydrosilylation Catalyzed by Ruthenium Complexes


24 Dec 2016

trans-hydrosilylation internal alkynes: notes/modifications

Summary:

Trost and Ball discovered the efficient Ru-catalyst for Markovnikov hydrosilylation of terminal alkynes as well as trans-hydrosilylation of internal alkynes. This reaction is the only general method for accessing geminal alkenylsilanes via ...

(4)

New Well-Defined Poly(2,7-fluorene) Derivatives:  Photoluminescence and Base Doping


17 Feb 2017

Robust synthesis of difuctional fluorene derivatives

Synthesized compounds 1, 2 and 8. These reactions were successfully reproduced at large scales (up to 10 times). 

  1. Synthesis of compound 1: Maintaining the reaction temperature at -78 oC is critical for achiving disubstitution. The crude materials...
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    (2)

Facile Synthesis of Structurally Diverse 3,3′-Disubstituted 1,1′-Binaphthyl-2,2′-diamines in Optically Pure Forms


09 Dec 2016

Simple BINAM ligand synthesis,improvements made for scale-up

Maruoka et al. developed a new synthetic route to access 3,3’-disubstituted BINAM compounds which are nitrogen derivatives of popular axial chiral ligands BINOL and BINAP. Their multi step approach involves in partial hydrogenation of BINAM to H8-BINAM,...

(2)

An Efficient Method for Solution-Phase Parallel Synthesis of 2-Quinoxalinol Salen Schiff-Base Ligands


09 Dec 2016

Excellent reproducibility, some improvements suggested

This article describes an efficient method for solution-phase parallel synthesis of 2-quinoxalinol salen Schiff-base ligands. The novelty of this article is the synthesis of a new category of ligands using Schiff-base condensation of an aldehyde with a...

(2)

Hydrodeoxygenation of acetic acid in a microreactor


01 Jan 2017

Feasible and efficient process. Easily reproducible.

Summary:

This study reports the hydrodeoxygenation (HDO) of acetic acid. The authors have chosen a packed bed microreactor for the purpose. The reason for put forward by the authors for choosing micro reactor is its efficiency in operation under reduced...

(2)

Nickel-Catalyzed Isomerization of 2-Methyl-3-butenenitrile†


09 Dec 2016

Modifications to catalytic isomerization of 2M3BN to 3PN

This article reports the catalytic isomerization of the branched isomer 2-methyl-3-butenenitrile (2M3BN) to the linear isomer 3-pentenenitrile (3PN) by DPEphos nickel species.

The species involved in the isomerization reaction were investigated by...

(2)

Catalytic Enantioselective Friedel-Crafts Alkylation of Indoles with Nitroalkenes by Using a Simple Thiourea Organocatalyst


17 Feb 2017

Good reported synthesis with room for improvement

Review:

This article describes the structure optimization and initial mechanistic understanding of a simple thiourea catalyst for the enantioselective alkylation of indoles with nitroalkenes.  The indole ring has proven to be a “privileged” structure in...

(2)

Nano ceria catalyzed synthesis of substituted benzimidazole, benzothiazole, and benzoxazole in aqueous media


24 Dec 2016

Work is good, descriptions could be better

Summary:

This paper reports a methodology for synthesis of substituted benzimidazole, benzothiazole, and benzoxazole in aqueous media. The method is novel in its approach of utilizing water as the medium, making it fit for a green chemistry protocol. The...

(2)

Silacyclohexadienylanionen bis- und tris-trimethylsilyl)-silacyclohexadiene


22 Feb 2017

Reproducible Reaction

Summary:

Synthesis of various silacycles has been reported. 

The Reaction of Interest:

Synthesis of t-BuSiHCl2 (18.5%, 50 mmol) via reaction of HSiCl3 (2 equiv) with t-BuLi.

Practical Observations:

  •  The reaction is reproducible, however 2...
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    (2)

Synthesis and Luminescence Properties of Colloidal YVO4:Eu Phosphors


05 Feb 2017

Synthesis useful for a laboratory course.

Solid state phosphors in the form of nanosized particles attract a lot of attention. This interest is of both fundamental and practical character. Ultrafine and homogeneous fluorescence particles can be used as biological labels and in the various lightning...

(2)

Particle size dependence of oxygen evolution reaction on nanocrystalline RuO2 and Ru0.8Co0.2O2−x


05 Feb 2017

A nice approach to synthesis of doped RuO2 nanopowders

Ruthenium oxide is one of the most active electrocatalytic material for oxygen evolution reaction (OER) and chlorine evolution reaction (CER). The attempts of improve its performance or to decrease the cost of the industrial electrodes resulted in many...

(2)

A fast and oxygen-promoted protocol for the ligand-free Suzuki reaction of 2-halogenated pyridines in aqueous media


08 Jan 2017

Best method to make various 2-phenylpyridine derivatives

Review :-

1) Synthesized all compounds from Table 1 (1-8) and Table 2 (1-13). I was able to achieve higher yields than the ones reported in this paper by doubling the catalyst concentration.

2) I used excess i.e 3 mol % Palladium acetate than the...

(2)

8-Dioxane ferra(III) bis(dicarbollide): A paramagnetic functional molecule as versatile building block for introduction of a Fe(III) centre into organic molecules


14 Dec 2016

Very useful paper for niche applications using metallacarboranes

Covalent attachment of 1,4-dioxane to beta born of ferracarborane sandwich complexes which can be easily outfitted with many organic functional groups. Procedure worked as reported, with moderate yields of 60-70%. Higher yields were achieved at smaller scales...

(2)

Synthesis, Characterization, and Catalase Activity of a Water-Soluble diMnIIIComplex of a Sulphonato-Substituted Schiff Base Ligand: An Efficient Catalyst for H2O2Disproportionation


23 Nov 2016

Review

This paper describes synthesis, characterization, and catalase activity of a water-soluble diMn(III) complex of a sulphonato-substituted Schiff-base ligand. DiMn(III) complex is highly efficient to disproportionate hydrogen peroxide in basic aqueous solutions...

(2)

High Current, Low Voltage Carbon Nanotube Enabled Vertical Organic Field Effect Transistors


16 Feb 2017

CN enabled VOFET potential to drive pixels in AMLED

In this manuscipt, a high current low voltage carbon nanotube (CN) enabled vertical organic field-effect transistor (VOFET) is reported that have the future potential to drive the pixels in active matrix organic light emitting diode (AMLED).

...

(3)

Stereocontrolled construction of the trans-tetrahydrofuran units in Annonaceous acetogenins


19 Dec 2016

Experimental not reproducible as written

Procedure for synthesis of intermediate 2 was repeated three times at identical scale and reaction conditions as described and then modified. When followed exact same procedure as-written (12 hours), desired compound was obtained in 14% yield (confirmed by...

(3)

Palladium-Catalyzed Silastannation of Secondary Propargylic Alcohols and their Derivatives


01 Nov 2016

Pd-catalyzed element-element addition to alkynes-a route to bis-functionalized alkenes

Tanner et al. has reported the silastannation reaction of several secondary terminal propargylic alcohols (protected and unprotected) with Pd2(dba)3·CHCl3/ Ph3P (1-2 equivalents of per Pd). Excellent regio and stereoselectivity (cis addition with tin always...

(2)

Design of Narrow-Bandgap Polymers. Syntheses and Properties of Monomers and Polymers Containing Aromatic-Donor and o -Quinoid-Acceptor Units


17 Feb 2017

Better yields with slight optimizations

This paper describes the synthesis and characterization of a series of thiophene- and N-methylpyrrole-based low band gap polymers incorporating o-quinoid acceptors such as thienopyrazine, quinoxaline, benzothiadiazole, pyrazinoquinoxaline,...

(2)

A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid


22 Feb 2017

Steven P. Cummings, Post-Doc

This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid.  Ultimately the synthesis provided greater yields, easier workups,...

(3)

Sulfonated Schiff base dinuclear and polymeric copper( ii ) complexes: crystal structures, magnetic properties and catalytic application in Henry reaction


24 Dec 2016

More aldehydes need to be tested for reproducibility

Summary:

This paper describes the synthesis of dinuclear and polymeric copper complexes of a sulfonated Schiff base ligand, 2-(2-pyridylmethyleneamino)benzenesulfonic acid. Also described, are the crystal structures, magnetic properties and catalytic...

(1)