Summary:
This paper reports a methodology for synthesis of substituted benzimidazole, benzothiazole, and benzoxazole in aqueous media. The method is novel in its approach of utilizing water as the medium, making it fit for a green chemistry protocol. The...
Summary:
Synthesis of various silacycles has been reported.
The Reaction of Interest:
Synthesis of t-BuSiHCl2 (18.5%, 50 mmol) via reaction of HSiCl3 (2 equiv) with t-BuLi.
Practical Observations:
Solid state phosphors in the form of nanosized particles attract a lot of attention. This interest is of both fundamental and practical character. Ultrafine and homogeneous fluorescence particles can be used as biological labels and in the various lightning...
Ruthenium oxide is one of the most active electrocatalytic material for oxygen evolution reaction (OER) and chlorine evolution reaction (CER). The attempts of improve its performance or to decrease the cost of the industrial electrodes resulted in many...
Review :-
1) Synthesized all compounds from Table 1 (1-8) and Table 2 (1-13). I was able to achieve higher yields than the ones reported in this paper by doubling the catalyst concentration.
2) I used excess i.e 3 mol % Palladium acetate than the...
Covalent attachment of 1,4-dioxane to beta born of ferracarborane sandwich complexes which can be easily outfitted with many organic functional groups. Procedure worked as reported, with moderate yields of 60-70%. Higher yields were achieved at smaller scales...
Summary:
Trost and Ball discovered the efficient Ru-catalyst for Markovnikov hydrosilylation of terminal alkynes as well as trans-hydrosilylation of internal alkynes. This reaction is the only general method for accessing geminal alkenylsilanes via ...
In this manuscipt, a high current low voltage carbon nanotube (CN) enabled vertical organic field-effect transistor (VOFET) is reported that have the future potential to drive the pixels in active matrix organic light emitting diode (AMLED).
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Procedure for synthesis of intermediate 2 was repeated three times at identical scale and reaction conditions as described and then modified. When followed exact same procedure as-written (12 hours), desired compound was obtained in 14% yield (confirmed by...
Tanner et al. has reported the silastannation reaction of several secondary terminal propargylic alcohols (protected and unprotected) with Pd2(dba)3·CHCl3/ Ph3P (1-2 equivalents of per Pd). Excellent regio and stereoselectivity (cis addition with tin always...
This paper describes the synthesis and characterization of a series of thiophene- and N-methylpyrrole-based low band gap polymers incorporating o-quinoid acceptors such as thienopyrazine, quinoxaline, benzothiadiazole, pyrazinoquinoxaline,...
This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups,...
Summary:
This paper describes the synthesis of dinuclear and polymeric copper complexes of a sulfonated Schiff base ligand, 2-(2-pyridylmethyleneamino)benzenesulfonic acid. Also described, are the crystal structures, magnetic properties and catalytic...
In one of my recent projects, I need find a method to convert diethyl malonate-d2 into 3-bromopropanol-d6. Following a literature reported procedure (Eur. J. Org. Chem. 2011, 3339–3346), diethyl malonate-d2 underwent lithium aluminum deuteride (LAD) reduction...
This review addresses the published preparation of compound 10c as listed in JOC 69, 4361 (2004). The stated preparation utilizes the inexpensive, commercially available diol, 6c. The preparation begins by combining the diol with one equivalent of TESCl in...
The article presents a facile and practical method to prepare fluorinated nucleosides, which are known for antitumor and antiviral activity, through introducing fluorine at the up-side of the 2’-carbon of nucleosides.
Particularly, I used this...
This reaction was repeated to prepare O-diphenylphosphinyl hydroxylamine as this compound was reported to be a "less explosive" electrophilic aminating agent. Note: a recent improved preparation has been reported. (DSC measurements of the isolated compound...
Synthesized 4,4’-didodecyl-2,2’-bithiophene (2b), and a similar compound 4,4’-dihexyl-2,2’-bithiophene (dhexbTH) following the procedure for the synthesis of 2a and 2b (given in supporting info.).
The yield for the synthesis of pure 2b was 50 %, which is...
Summary:
An easy, green, efficient and simple for synthesis of derivatives of benzimidazole-, benzothiazole- and benzoxazole-2-thiol has been described. Although previous methods are available in literature for synthesis of such compounds, this method...
The article by Strunz and co-workers reported a total synthesis of sterpurene and the bioactivity of some related sesquiterpene metabolites.
I am particularly interested in the preparation of intermediate 14 (4-step synthesis, Scheme 3) since it could...