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Summary
Researchers discovered a protein which triggers satellite cells to proliferate and heal. In sh with severe muscle damage, injection of NAMPT led to the regeneration of muscle and the return of normal movement. This study demonstrates that NAMPT, can...
Summary:
This paper reports the chemosensing properties of a commercially available fluorescent probe, 1,8-diamino naphthalene for copper ion detection in the aqueous medium and its application in bioimaging. The proposed mechanism involves fluorescence...
This paper by Erlanson and colleagues describes the disulfide tethering technique, which has proven to be a reproducible and versatile method for finding fragment hits. The main advance is the covalent targeting of the fragment library to a specific site on a...
The premise of the article is to summarize the ways in which stimuli- responsive polymersomes are involved in the creation of nanocarriers, as well as their contribution to each nanocarrier's performance in varied environments or stimuli. Polymersomes are...
Summary:
The first simple cyclic silyl peroxide, namely 1,1,4,4,-tetramethyl-1,4-disila-2,3-dioxane, was prepared by classical synthetic methodology from its corresponding cyclic disilazane and the urea complex of hydrogen peroxide.
The Reaction of...
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This paper describes the analysis of methods and basis sets for theoretical calculations on oxorhenium(V) complexes. A variety of ligand systems with different coordinating atoms (N, O, P, S, Cl, and Se) were incorporated into this study. Two...
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A simple, convenient, and environment-friendly method for synthesis of 1,2-disubstituted benzimidazoles in high yields under extremely mild conditions, has been described. The methodology described, involves condensation of o-phenylenediamine...
Summary
Researchers discovered a protein which triggers satellite cells to proliferate and heal. In fish with severe muscle damage, injection of NAMPT led to the regeneration of muscle and the return of normal movement. This study demonstrates that NAMPT,...
The presented route provides an efficient and highly reproducible method to obtain penultimate allyl-protected intermediates of 3-Substituted 5-Amino-1-(chloromethyl)-1,2-dihydro-3H-benzo[e]indoles (amino-CBIs). De-allylation utilizing Grubbs carbene proved...
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This paper describes a novel way to measure core body temperature using a three-dimensional (3D) printed wearable “earable” smart device. The device is designed to be worn on the ear and track core body temperature from the tympanic membrane (i.e.,...
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A practical synthesis of 11-membered C2-symmetric binaphthyl ketone (R)-1, a catalyst for asymmetric epoxidation, was developed. This manuscript describes the single example of chiral resolution of (±)-1,1’-Binaphthyl-2,2’-dicarboxylic acid [(±)-6...
This article reported the synthesis of different sulfonyl chloride of polynuclear heterocyclic compounds which are very important intermediates to form different derivatives like sulfonates. Unfortunately, this paper is lacking a complete isolation and...
Review:
This article/communication described the preapration of 2 and 4-quinolinecarboxaldehyde using 2 and 4-methylquinoline in the presence of selenous acid in refluxing dioxane. While the procedure explicitly stated the use of selenous acid, selenium...
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This paper reports an efficient method for synthesising benzimidazoles through cascade reactions of o-haloacetoanilide derivatives with amidine hydrochlorides. 10 mol % CuBr was used as the catalyst and Cs2CO3 as the base. The reactions were...
Summary:
An efficient and green method for synthesis of 2 substituted benzimidazoles has been described. Despite previous methods being available in literature for synthesis of such compounds, the ease of operation, use of common and non-toxic solvent and...
This paper describes the development and use of a CRISPR based diagnostic for Mycobacterium tuberculosis (Mtb). I was particularly interested in this paper because it hits all the things which my research is focused on – Mtb, diagnostics, and the practical...
Yttrium oxysulfide – Y2O2S is knows an excellent host material for the Eu(III) activated red emission phosphor, which has been used for decades in the CRT displays and conventional TV due to its excellent brightness, color purity, life time and compatibility...
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This paper reports an efficient method for aldol condensation between a methyl 3-hydroxy-5-oxohexanoate derivative and a pyrimidine carbaldehyde comprising the core structure of rosuvastatin. The authors have described the method as an...
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A framework for improving knee rehabilitation and reducing ACL injury incidence and reinjury rates post anterior cruciate ligament reconstruction has been described. The framework encourages a global approach, whereby ‘proximal’ is not confined to...
Summary:
This paper describes a novel way to measure core body temperature using a three-dimensional (3D) printed wearable “earable” smart device. The device is designed to be worn on the ear and track core body temperature from the tympanic membrane (i.e.,...