This paper describes amazingly shortest synthesis for such a complex macrolide. Geldanamycin was synthesized in 20 steps using key steps such as Cu-catalyzed intramolecular amidation. I have used synthetic strategy to synthesize prodrug of geldanamycin with little modification amidation. Actually CuI was interfering with my substrate so I changed Cu to Palladium chemistry (Buchwald amination). Great work.