• 10.1021/jo301293w
  • The Journal of Organic Chemistry
  • Volume 77
  • August 2012
  • pp 7124-7128

Ir-Catalyzed Direct Borylation at the 4-Position of Pyrene

Useful experimental

Details


1. Synthesized compound 1 and another similar compound using the procedure described in this article.

2. Used 0.2 mmol Iridium instead of 0.1 mmol as reported. The reaction was monitored by TLC and after 48 hrs, all starting materials was consumed. The product was purified by column chromatography (using DCM:hexane 3:7). Yield: 45-50%.

3. Used 20 mmol of B2pin2, same procedure was followed and the diborylated product (instead of 1) was purified by column chromatography (DCM:hexane 1:9) in 40% yield.



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