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With Tag: N-aryl Anthranilic Acid

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Regioselective Copper-Catalyzed Amination of Chlorobenzoic Acids:  Synthesis and Solid-State Structures ofN-Aryl Anthranilic Acid Derivatives

Xuefeng Mei, Adam T August, Christian Wolf
The Journal of Organic Chemistry | 2006 | 10.1021/jo0518809

A chemo- and regioselective copper-catalyzed cross-coupling reaction for effective amination of 2-chlorobenzoic acids with aniline derivatives has been developed. The method eliminates the need for acid protection and produces a wide range of N-aryl...

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