Papers

With Tag: Drug Discovery

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Potassium ion channels and human disease: phenotypes to drug targets?

Current Opinion in Biotechnology | 1998 | 10.1016/S0958-1669(98)80133-X

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Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats

Wenliang Yang, Lin Zhang, Xiaoquan Liu, Yan Wang, Yuancheng Chen, Wanwen Cao, Yuan Cao, Bobo Chang
Acta Pharmacologica Sinica | 2010 | 10.1038/aps.2010.27

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Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid In vitro

An Qin, Xiuguo Han, Qiming Fan, Han Qiao, Tingting Tang, Yugang Wang, Wei Yan, Tingyu Wang
Acta Pharmacologica Sinica | 2015 | 10.1038/aps.2015.42

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Efficacy of subantimicrobial-dose doxycycline against nitrosative stress in chronic periodontitis

Alexandra Cr Abreve, Sandu Florin Alb, Alina Elena Pârvu, M Taulescu, Ciun
Acta Pharmacologica Sinica | 2013 | 10.1038/aps.2012.129

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Perspectives of antimony compounds in oncology

Diego Perez, J L Arias, Armando Cabrera, Pankaj Sharma, Noe Rosas
Acta Pharmacologica Sinica | 2008 | 10.1111/j.1745-7254.2008.00818.x

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A hearty solution for acute myeloid leukemia.

Yiju Hung, H Eugene Liu
Acta Pharmacologica Sinica | 2012 | 10.1038/aps.2011.197

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Involvement of Bcl-2, Src, and ER|[alpha]| in gossypol-mediated growth inhibition and apoptosis in human uterine leiomyoma and myometrial cells

Jieyun Zhou, Yan Zhu, Yang Cao, Lin Cao, Tingting Zhang, Jianfeng Zhang, Shuwu Xie
Acta Pharmacologica Sinica | 2010 | 10.1038/aps.2010.153

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Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1.

Rong Zeng, Shuai Zhao, Guohui Cui, Yan Chen
Acta Pharmacologica Sinica | 2012 | 10.1038/aps.2011.143

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The effect of poor compliance on the pharmacokinetics of carbamazepine and its epoxide metabolite using Monte Carlo simulation

Junjie Ding, Zheng Jiao, Yi Wang, Yunjian Zhang
Acta Pharmacologica Sinica | 2012 | 10.1038/aps.2012.135

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Permeation-enhancing effects of chitosan formulations on recombinant hirudin-2 by nasal delivery in vitro and in vivo

Yujie Zhang, Changhua Ma, Wanliang Lu, Xiaoliang Wang, Jianning Sun, Qiang Zhang, Xuan Zhang
Acta Pharmacologica Sinica | 2005 | 10.1111/j.1745-7254.2005.00174.x

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Prenatal nicotine exposure enhances the susceptibility to metabolic syndrome in adult offspring rats fed high-fat diet via alteration of HPA axis-associated neuroendocrine metabolic programming

Youying Lei, Li Zhang, Liping Xia, Lang Shen, Hui Wang, Jacques Magdalou, Dan Xu, Lian Liu
Acta Pharmacologica Sinica | 2013 | 10.1038/aps.2013.171

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Selective |[alpha]|1B- and |[alpha]|1D-adrenoceptor antagonists suppress noradrenaline-induced activation, proliferation and ECM secretion of rat hepatic stellate cells in vitro

Yong Ma, Wei Wei, Tilong Ding, Tingting Liu
Acta Pharmacologica Sinica | 2014 | 10.1038/aps.2014.84

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Involvement of REST corepressor 3 in prognosis of human hepatitis B

Jihua Xue, Zhi Chen, Xiaowei Xu, Shanshan Wu, Feng Chen, Min Zheng
Acta Pharmacologica Sinica | 2011 | 10.1038/aps.2011.49

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Astragalus polysaccharides suppress ICAM-1 and VCAM-1 expression in TNF-|[alpha]|-treated human vascular endothelial cells by blocking NF-|[kappa]|B activation

Yong Man, Yuan Cao, Jian Li, Tao Shen, Yue Qiao, Yajun Lin, Beidong Chen, Shu Wang, Yang Ruan, Yuping Zhu
Acta Pharmacologica Sinica | 2013 | 10.1038/aps.2013.46

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Identification of human dopamine D1‐like receptor agonist using a cell‐based functional assay1

X U Zhiliang, Nan Jiang, H U Yinghe, Keqing Ouyang, Shaoxi Cai
Acta Pharmacologica Sinica | 2005 | 10.1111/j.1745-7254.2005.00199.x

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Deferiprone protects the isolated atria from cardiotoxicity induced by doxorubicin

Liang Jin, X U Lingjie, Gang Wei, Hong Pan, L U Weiyue, Aozhen Zhang, L I Pingping
Acta Pharmacologica Sinica | 2006 | 10.1111/j.1745-7254.2006.00409.x

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Functional comparison of the reverse mode of Na+/Ca2+ exchangers NCX1.1 and NCX1.5 expressed in CHO cells

Weiping Wang, Nan Feng, Xiaoliang Wang, Yan Long, Shiping Ma, Hui Yuan, Ling Wang
Acta Pharmacologica Sinica | 2013 | 10.1038/aps.2013.4

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Toll-like receptor 7/8 agonist resiquimod induces late preconditioning in neonatal cardiac myocytes

Sha Liu, Yongyi Wang, Song Xue, Feng Lian, Wengang Yang
Acta Pharmacologica Sinica | 2011 | 10.1038/aps.2011.6

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Characterization of the anticancer effects of S115, a novel heteroaromatic thiosemicarbazone compound, in vitro and in vivo.

Lin Xiao, Yuqiong Dong, Yulong Yao, Quanhai Liu, Minyu Liu, Ming Yin, Ying Liu, Li Cai, Weixia Xiong
Acta Pharmacologica Sinica | 2014 | 10.1038/aps.2014.71

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Coexistence of qnrB4 and qnrS1 in a clinical strain of Klebsiella pneumoniae

Minggui Wang, X U Xiaogang, Demei Zhu, H U Fupin
Acta Pharmacologica Sinica | 2008 | 10.1111/j.1745-7254.2008.00757.x

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