Rajasingh, P.; Cohen, R.; Shirman, E.; Shimon, L. J. W.; Rybtchinski, B. The Journal of Organic Chemistry | 2007 | 10.1021/jo070367n
A novel method for the bromination of perylene diimides, PDI (1), under mild conditions is reported. Variation of the reaction conditions allows mono- and dibromination of PDIs to afford 2 and 3 (these can be separated through standard procedures) or...
Xiao-Liang Yang, Chun-Mei Xu, Shao-Miao Lin, Jiu-Xi Chen, Jin-Chang Ding, Hua-Yue Wu, Wei-Ke Su Journal of the Brazilian Chemical Society | 2010 | 10.1590/s0103-50532010000100007
Steven D. Gore, Patrick M. Woster, Deepak Gupta, Sheeba Varghese, Tiffany Baran, Robert A. Casero, Anchalee Jiemjit Journal of Medicinal Chemistry | 2005 | 10.1021/jm0505009
The reversible acetylation of histones is critical for regulation of eukaryotic gene expression. The histone deacetylase inhibitors trichostatin (TSA, 1), MS-275 (2) and suberoylanilide hydroxamic acid (SAHA, 3) arrest growth in transformed cells and in human...
G Märkl, H. Höllriegl, W. Schlosser Journal of Organometallic Chemistry | 1984 | 10.1016/s0022-328x(00)98691-1
1,1-Dialkyl(1,1-diaryl)-4-R-1-silacyclohexadienyl anions ( 1 ) are available by ether cleavage of the corresponding, 1,1-dialkyl(1,1-diaryl)-4-methoxy-4-R-1-silacyclohexa-2,5-dienes ( 4 ), or by deprotonation of the...
Yves R. Dumond, Rhonda L. Baker, Jean-Luc Montchamp Organic Letters | 2000 | 10.1021/ol006434g
Monosubstituted phosphinic acids are esterified with orthosilicates in excellent yields. Phosphinylidene-containing acids react selectively under these conditions, while disubstituted phosphinic acids and phosphonic acids remain unchanged. One-pot procedures...
Alexandra Chaumonnot, Franck Lamy, Sylviane Sabo-Etienne, Bruno Donnadieu, Bruno Chaudret, Jean-Claude Barthelat, Jean-Christophe Galland Organometallics | 2004 | 10.1021/om049706i
Isomerization of 2-methyl-3-butenenitrile to 3-pentenenitrile is catalyzed by nickel π-allyl cyanide complexes. The C−CN bond breaking is a key step in the catalytic mechanism, as evidenced by in situ NMR monitoring and DFT studies.
Kye Jung Shin, Hyung Ryong Moon, Clifford George, Victor E. Marquez The Journal of Organic Chemistry | 2000 | 10.1021/jo9917691
An intramolecular olefin keto-carbene cycloaddition reaction created the bicyclo[3.1.0]hexane template 10 that was necessary for the synthesis of carbocyclic amine 15. This amine is a direct precursor to a family of rigid nucleosides that are conformationally...
Eilaf Ahmed, Selvam Subramaniyan, Felix S. Kim, Hao Xin, Samson A. Jenekhe Macromolecules | 2011 | 10.1021/ma201128x
Six new donor–acceptor copolymers based on benzobisthiazole and various donor moieties (dithienosilole, dithienopyrrole, cyclopentadithiophene, carbazole, benzodithiophene, and bithiophene) were synthesized, characterized, and used in field-effect transistors...
Singh, C.; Hassam, M.; Verma, V. P.; Singh, S. A.; Naikade, N. K.; Puri, S. K.; Maulik, P. R.; Kant, R. Journal of Medicinal Chemistry | 2012 | 10.1021/jm301323k
A new series of bile acid-based trioxanes 23a–d, 24a–d, 25a–d, 26a, 26b, and 26d have been synthesized and assessed for their antimalarial activity against multidrug-resistant Plasmodium yoelii in Swiss mice by oral route. The antimalarial activity of these...
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