A practical synthesis of 11-membered C 2-symmetric binaphthyl ketone (R)-1, a catalyst for asymmetric epoxidation, was developed. (±)-1,1'-Binaphthyl-2,2'-dicarboxylic acid [(±)-6] was efficiently resolved by (R)-(-)-1-cyclohexylethylamine to give (R)-6 in...
Michelle J. Kim, Jennifer M. Michaud, Renee Williams, Byron Pedler Sherwood, Robert Pomeroy, Farooq Azam, Michael Burkart, Timothy H. Bertram Biochemistry | 2012 | 10.1021/bi300797q
Xuefeng Mei, Adam T August, Christian Wolf The Journal of Organic Chemistry | 2006 | 10.1021/jo0518809
A chemo- and regioselective copper-catalyzed cross-coupling reaction for effective amination of 2-chlorobenzoic acids with aniline derivatives has been developed. The method eliminates the need for acid protection and produces a wide range of N-aryl...
J. Jayabharathi, V. Thanikachalam, K. Jayamoorthy, R. Sathishkumar Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2012 | 10.1016/j.saa.2012.06.012
Shi-Kai Tian, Zhi-Min Wang, Jian-Kang Jiang, Min Shi Tetrahedron: Asymmetry | 1999 | 10.1016/s0957-4166(99)00259-1
Abstract
An efficient synthetic method for the construction of trans-tetrahydrofuran (THF) unit from trans-1,5,9-decatriene was successfully developed by means of Sharpless AD reactions and oxidative cyclizations catalyzed by Co(modp)2 under an oxygen...
George M. Strunz, Richard Bethell, Michael T. Dumas, Nick Boyonoski Canadian Journal of Chemistry | 1997 | 10.1139/v97-090
Sterpurene, a sesquiterpene hydrocarbon metabolite of Chondrostereumpurpureum, a plant pathogen and potential mycoherbicide, was synthesized by a six-step sequence, in 33% overall yield. The key steps were a thermal [4 + 2] (Diels–Alder) cycloaddition...
Subramaniam Arumugam, Dale McLeod, John G. Verkade The Journal of Organic Chemistry | 1998 | 10.1021/jo972350i
The symmetric active-methylene compounds CH 2 (CO 2 Et) 2 and CH 2 [C(O)Me] 2 are selectively monoalkylated in the presence of 1.1 equiv of a variety of alkyl halides and 1 equiv of the nonionic superbase P(MeNCH 2 CH 2 ) 3 N in 85−98% yields in 30 min at...
