Synthesis of 9-(2-deoxy-2-fluoro--D-arabinofuranosyl)adenine bearing a selectively removable protecting group

  • Chemical & pharmaceutical bulletin
  • p 966-970, Volume 47, Issue 7,


Synthesis of 2'-fluorinated Adenosine

The article presents a facile and practical method to prepare fluorinated nucleosides, which are known for antitumor and antiviral activity, through introducing fluorine at the up-side of the 2’-carbon of nucleosides.

Particularly, I used this synthetic route to obtain...