Eco-friendly synthesis of 2-substituted benzothiazoles catalyzed by cetyltrimethyl ammonium bromide (CTAB) in water

  • 10.1590/s0103-50532010000100007
  • Journal of the Brazilian Chemical Society
  • p 37-42, Volume 21, Issue 1,
  • journal-article


Innovative but has errors which affects reproducibility


This paper reports a CTAB-catalyzed method developed for the synthesis of 2-substituted benzothiazoles by the condensation of 2-aminothiophenol with aldehydes (RCHO: R = Alkyl, Aryl, Heteroaryl, 2-Arylformyl). Use of cetyltrimethyl ammonium bromide (CTAB) in an “on...