A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend , David Fengas , M. Jonathan Fray

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DOI 10.1081/scc-200050350

Journal Synthetic Communications
Location p 657-662, Volume 35, Issue 5, 2005
Publication Type journal-article

Tags 3, 3-difluorocyclobutane carboxylic acid, synthesis, lipophilicity, organic chemistry
Publisher Link Click Here

Paper Abstract Abstract: We reported a straightforward, three step synthesis of 3,3-difluorocyclobutane carboxylic acid.

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08 Jul 2017

Peter Boyle

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22 Feb 2017

Steven Cummings

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Steven P. Cummings, Post-Doc

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This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups, and a less dangerous...

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A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend , David Fengas , M. Jonathan Fray

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Steven P. Cummings, Post-Doc

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