A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend, David Fengas, M. Jonathan Fray

Add Review (press R) Confirm Authorship

Paper Rating

Logic / Design

Reproducibility

Clarity

Versatility

Paper Details

DOI 10.1081/scc-200050350

Journal Synthetic Communications
Location p 657-662, Volume 35, Issue 5, 2005
Publication Type journal-article

Tags 3, 3-difluorocyclobutane carboxylic acid, synthesis, lipophilicity, organic chemistry
Publisher Link Click Here

Paper Abstract Abstract: We reported a straightforward, three step synthesis of 3,3-difluorocyclobutane carboxylic acid.

Review

22 Feb 2017

Steven Cummings

(3)

Steven P. Cummings, Post-Doc

Logic / Design

Reproducibility

Clarity

Versatility

This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups, and a less dangerous...

/paper/doi/10.1081/scc-200050350	0.000000	0.000000
INIT	0.000266	0.000266
_initView	0.001077	0.001343
_initViewBasic	0.000197	0.001540
_initSiteModules	0.000229	0.001769
_initRouters	0.000168	0.001937
Sess +	0.001582	0.003519
Sess _	0.000145	0.003664
pre dispatch _	0.000171	0.003835
LC::doiAction START	0.000230	0.004065
LC::doiAction END to showListing	0.192955	0.197020
LC::showListing START	0.000006	0.197026
LC::showListing get reviews START	0.000021	0.197047
ES Review Search START	0.000625	0.197672
ES Review Search END	0.006467	0.204139
LC::showListing get reviews END	0.000917	0.205056
Done	0.025871	0.230927

Loading...

A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend, David Fengas, M. Jonathan Fray

Overall Rating

Review

Steven P. Cummings, Post-Doc

Recently Reviewed

Has Cited

Cited by

Sign In With