A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend, David Fengas, M. Jonathan Fray

Add Review (press R) Confirm Authorship

Paper Rating

Logic / Design

Reproducibility

Clarity

Versatility

Paper Details

DOI 10.1081/scc-200050350

Journal Synthetic Communications
Location p 657-662, Volume 35, Issue 5, 2005
Publication Type journal-article

Tags 3, 3-difluorocyclobutane carboxylic acid, synthesis, lipophilicity, organic chemistry
Publisher Link Click Here

Paper Abstract Abstract: We reported a straightforward, three step synthesis of 3,3-difluorocyclobutane carboxylic acid.

Review

22 Feb 2017

Steven Cummings

(3)

Steven P. Cummings, Post-Doc

Logic / Design

Reproducibility

Clarity

Versatility

This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups, and a less dangerous...

/paper/doi/10.1081/scc-200050350	0.000000	0.000000
INIT	0.000269	0.000269
_initView	0.001150	0.001419
_initViewBasic	0.000190	0.001609
_initSiteModules	0.000188	0.001797
_initRouters	0.000171	0.001968
Sess +	0.001500	0.003468
Sess _	0.000105	0.003573
pre dispatch _	0.000141	0.003714
LC::doiAction START	0.000220	0.003934
LC::doiAction END to showListing	0.127589	0.131523
LC::showListing START	0.000004	0.131527
LC::showListing get reviews START	0.000016	0.131543
ES Review Search START	0.000762	0.132305
ES Review Search END	0.008535	0.140840
LC::showListing get reviews END	0.000792	0.141632
Done	0.023971	0.165603

Loading...

A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend, David Fengas, M. Jonathan Fray

Overall Rating

Review

Steven P. Cummings, Post-Doc

Recently Reviewed

Has Cited

Cited by

Sign In With