A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend; David Fengas;, M. Jonathan Fray

Add Review (press R) Confirm Authorship

Paper Rating

Logic / Design

Reproducibility

Clarity

Versatility

Paper Details

DOI 10.1081/scc-200050350

Journal Synthetic Communications
Location p 657-662, Volume 35, Issue 5, 2005
Publication Type journal-article

Tags 3, 3-difluorocyclobutane carboxylic acid, synthesis, lipophilicity, organic chemistry
Publisher Link Click Here

Paper Abstract Abstract: We reported a straightforward, three step synthesis of 3,3-difluorocyclobutane carboxylic acid.

Review

22 Feb 2017

Steven Cummings

(3)

Steven P. Cummings, Post-Doc

Logic / Design

Reproducibility

Clarity

Versatility

This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups, and a less dangerous...

/paper/doi/10.1081/scc-200050350	0.000000	0.000000
INIT	0.000177	0.000177
_initView	0.000942	0.001119
_initViewBasic	0.000174	0.001293
_initSiteModules	0.000146	0.001439
_initRouters	0.000127	0.001566
Sess +	0.001329	0.002895
Sess _	0.000120	0.003015
pre dispatch _	0.000127	0.003142
LC::doiAction START	0.000222	0.003364
LC::doiAction END to showListing	0.164406	0.167770
LC::showListing START	0.000005	0.167775
LC::showListing get reviews START	0.000018	0.167793
ES Review Search START	0.000561	0.168354
ES Review Search END	0.008839	0.177193
LC::showListing get reviews END	0.000800	0.177993
Done	0.025042	0.203035

Loading...

A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend; David Fengas;, M. Jonathan Fray

Overall Rating

Review

Steven P. Cummings, Post-Doc

Recently Reviewed

Has Cited

Cited by

Sign In With