A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

  • 10.1081/scc-200050350
  • Synthetic Communications
  • p 657-662, Volume 35, Issue 5,
  • journal-article
Abstract: We reported a straightforward, three step synthesis of 3,3-difluorocyclobutane carboxylic acid.


Steven P. Cummings, Post-Doc

This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid.  Ultimately the synthesis provided greater yields, easier workups, and a less dangerous...