A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend; David Fengas;, M. Jonathan Fray

Add Review (press R) Confirm Authorship

Paper Rating

Logic / Design

Reproducibility

Clarity

Versatility

Paper Details

DOI 10.1081/scc-200050350

Journal Synthetic Communications
Location p 657-662, Volume 35, Issue 5, 2005
Publication Type journal-article

Tags 3, 3-difluorocyclobutane carboxylic acid, synthesis, lipophilicity, organic chemistry
Publisher Link Click Here

Paper Abstract Abstract: We reported a straightforward, three step synthesis of 3,3-difluorocyclobutane carboxylic acid.

Review

22 Feb 2017

Steven Cummings

(3)

Steven P. Cummings, Post-Doc

Logic / Design

Reproducibility

Clarity

Versatility

This communication was outstanding in providing a vast improvement to a very dangerous and potentially synthetically challenging method in obtaining 3,3-difluorocyclobutane carboxylic acid. Ultimately the synthesis provided greater yields, easier workups, and a less dangerous...

/paper/doi/10.1081/scc-200050350	0.000000	0.000000
INIT	0.000181	0.000181
_initView	0.000798	0.000979
_initViewBasic	0.000186	0.001165
_initSiteModules	0.000148	0.001313
_initRouters	0.000130	0.001443
Sess +	0.001315	0.002758
Sess _	0.000227	0.002985
pre dispatch _	0.000131	0.003116
LC::doiAction START	0.000323	0.003439
LC::doiAction END to showListing	0.215915	0.219354
LC::showListing START	0.000005	0.219359
LC::showListing get reviews START	0.000020	0.219379
ES Review Search START	0.000667	0.220046
ES Review Search END	0.008594	0.228640
LC::showListing get reviews END	0.000882	0.229522
Done	0.024907	0.254429

Loading...

A Practical Synthesis of 3,3‐Difluorocyclobutane Carboxylic Acid

Dirk Elend; David Fengas;, M. Jonathan Fray

Overall Rating

Review

Steven P. Cummings, Post-Doc

Recently Reviewed

Has Cited

Cited by

Sign In With