Reversible RNA acylation for control of CRISPR–Cas9 gene editing

  • 10.1039/c9sc03639c
  • Chemical Science
  • p 1011-1016, Volume 11, Issue 4,
  • journal-article

We report the development of post-transcriptional chemical methods that enable control over CRISPR–Cas9 gene editing activity both in in vitro assays and in living cells.