A fast protocol has been developed for the construction of 2-aryl-substituted pyridine derivatives by the oxygen-promoted, ligand-free, Pd(OAc)2-catalyzed Suzuki reaction of 2-halogenated pyridines in aqueous isopropanol.
1) Synthesized all compounds from Table 1 (1-8) and Table 2 (1-13). I was able to achieve higher yields than the ones reported in this paper by doubling the catalyst concentration.
2) I used excess i.e 3 mol % Palladium acetate than the reported 1.5 mol % for...
Best method to make various 2-phenylpyridine derivatives
Review :-
1) Synthesized all compounds from Table 1 (1-8) and Table 2 (1-13). I was able to achieve higher yields than the ones reported in this paper by doubling the catalyst concentration.
2) I used excess i.e 3 mol % Palladium acetate than the reported 1.5 mol % for...