Palladium-Catalyzed Formal Hydroacylation of Allenes Employing Acid Chlorides and Hydrosilanes

  • 10.1021/ol400862k
  • Org. Lett.
  • p 2-2, 15 (9), Issue 9,
  • Letter
The palladium-catalyzed formal hydroacylation of allenes employing acid chlorides and hydrosilanes has been achieved. The reactions proceed with commercially available Pd(OAc) 2 as a catalyst and HSi(iPr) 3 as a reducing reagent, giving the corresponding α,β-unsaturated ketones regio- and stereoselectively.