Copper-Catalyzed Trifluoromethylation of Aryl and Vinyl Boronic Acids with An Electrophilic Trifluoromethylating Reagent

  • 10.1021/ol2005903
  • Org. Lett.
  • p 2-3, 13 (9), Issue 9,
  • Letter
A copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with Togni’s reagent was described. The reaction proceeded in good to excellent yields for a range of different substrates including heteroarylboronic acids and substrates with a variety of functional groups under mild reaction conditions.