Desymmetrization Reactions: Efficient Preparation of Unsymmetrically Substituted Linker Molecules

Alan W. Schwabacher , James W. Lane , Matthew W. Schiesher , Krista M. Leigh , Christopher W. Johnson

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DOI 10.1021/jo971802o

Journal The Journal of Organic Chemistry
Location p 1727-1729, Volume 63, Issue 5, 1998
Publication Type journal-article

Tags organic chemistry
Publisher Link Click Here

Review

09 Dec 2016

Ronald Okoth

(0)

Innovative,one-pot method to synthesize bifunctional linkers

Reproducibility

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Innovation

The paper presents an innovative way to synthesis bi functional linker (in this case azido-amine linkers). The method used described as concurrent reaction-extraction taking place in one pot has attracted a lot of attention. In the synthesis of compound 1 a linker containing an...

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Desymmetrization Reactions: Efficient Preparation of Unsymmetrically Substituted Linker Molecules

Alan W. Schwabacher , James W. Lane , Matthew W. Schiesher , Krista M. Leigh , Christopher W. Johnson

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Innovative,one-pot method to synthesize bifunctional linkers

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