Desymmetrization Reactions:  Efficient Preparation of Unsymmetrically Substituted Linker Molecules

  • 10.1021/jo971802o
  • The Journal of Organic Chemistry
  • p 1727-1729, Volume 63, Issue 5,
  • journal-article


Innovative,one-pot method to synthesize bifunctional linkers

The paper presents an innovative way to synthesis bi functional linker (in this case azido-amine linkers). The method used described as concurrent reaction-extraction taking place in one pot has attracted a lot of attention. In the synthesis of compound 1 a linker containing an...