Ir-Catalyzed Direct Borylation at the 4-Position of Pyrene

  • 10.1021/jo301293w
  • The Journal of Organic Chemistry
  • p 7124-7128, Volume 77, Issue 16,
  • journal-article
The first direct borylation of a C–H bond at the 4-position of pyrene was achieved using [Ir(COD)Cl] 2 /dtbpy as the catalyst precursor and B 2 pin 2 as the boron source. The position-related photophysical properties of pyrene derivatives are reported.


Useful experimental

1. Synthesized compound 1 and another similar compound using the procedure described in this article.

2. Used 0.2 mmol Iridium instead of 0.1 mmol as reported. The reaction was monitored by TLC and after 48 hrs, all starting materials was consumed. The product was purified by...