Enantioselective formation of functionalized 1,3-disubstituted allenes: synthesis of .alpha.-allenic .omega.-carbomethoxy alcohols of high optical purity

Owen W. Gooding, Colin C. Beard, David Y. Jackson, Douglas L. Wren, Gary F. Cooper

Paper Rating

Reproducibility

Clarity

Versatility

Paper Details

09 Dec 2016

Anonymous

(1)

Reproducibility

Clarity

Versatility

Synthesized (3) and a compound similar to (4) but with protection on -OH groups.

For (3): Dissolving CBr4 in dichloromethane instead of pyridine gave a better yield as it involved using only one solvent throughout the reaction.

For (4): The formation of alkyne group was...

Add Review

/paper/doi/10.1021/jo00003a033	0.000000	0.000000
INIT	0.000213	0.000213
_initView	0.001037	0.001250
_initViewBasic	0.000159	0.001409
_initSiteModules	0.000157	0.001566
_initRouters	0.000145	0.001711
Sess +	0.001391	0.003102
Sess _	0.000103	0.003205
pre dispatch _	0.000134	0.003339
LC::doiAction START	0.000211	0.003550
LC::doiAction END to showListing	0.170183	0.173733
LC::showListing START	0.000003	0.173736
LC::showListing get reviews START	0.000037	0.173773
ES Review Search START	0.000550	0.174323
ES Review Search END	0.007505	0.181828
LC::showListing get reviews END	0.000890	0.182718
Done	0.025892	0.208610