Tetraalkylammonium salts in heck-type reactions using an alkali metal hydrogen carbonate or an alkali metal acetate as the base

Tuyet Jeffery , Jean-christophe Galland

Add Review (press R) Confirm Authorship

Paper Rating

Reproducibility

Clarity

Versatility

Paper Details

DOI 10.1016/s0040-4039(00)73124-8

Journal Tetrahedron Letters
Location p 4103-4106, Volume 35, Issue 24, 1994
Publication Type journal-article

Tags cross coupling, heck reaction, alkali metals, organic chemistry, biochemistry, drug discovery
Publisher Link Click Here

Review

19 Dec 2016

Andrew Lin

(5)

Seminal paper for phase-transfer Heck-Mizoroki cross coupling

Reproducibility

Clarity

Versatility

A pinacle reaction of the synthesis required the cross coupling off a two highly heteroatom functionalised fragments, the use of traditional Heck conditions, such as palladium (II) acetate, triphenyl phosphine and triethylamine afforded poor yields and irreproducibility. Upon...

/paper/doi/10.1016/s0040-4039(00)73124-8	0.000000	0.000000
INIT	0.000166	0.000166
_initView	0.000798	0.000964
_initViewBasic	0.000162	0.001126
_initSiteModules	0.000176	0.001302
_initRouters	0.000169	0.001471
Sess +	0.001279	0.002750
Sess _	0.000112	0.002862
pre dispatch _	0.000130	0.002992
LC::doiAction START	0.000230	0.003222
LC::doiAction END to showListing	0.178754	0.181976
LC::showListing START	0.000005	0.181981
LC::showListing get reviews START	0.000019	0.182000
ES Review Search START	0.000673	0.182673
ES Review Search END	0.006199	0.188872
LC::showListing get reviews END	0.000826	0.189698
Done	0.026978	0.216676

Loading...

Tetraalkylammonium salts in heck-type reactions using an alkali metal hydrogen carbonate or an alkali metal acetate as the base

Tuyet Jeffery , Jean-christophe Galland

Overall Rating

Review

Seminal paper for phase-transfer Heck-Mizoroki cross coupling

Recently Reviewed

Has Cited

Cited by

Sign In With