Tetraalkylammonium salts in heck-type reactions using an alkali metal hydrogen carbonate or an alkali metal acetate as the base

Tuyet Jeffery, Jean-Christophe Galland

Add Review (press R) Confirm Authorship

Paper Rating

Reproducibility

Clarity

Versatility

Paper Details

DOI 10.1016/s0040-4039(00)73124-8

Journal Tetrahedron Letters
Location p 4103-4106, Volume 35, Issue 24, 1994
Publication Type journal-article

Tags cross coupling, heck reaction, alkali metals, organic chemistry, biochemistry, drug discovery
Publisher Link Click Here

Review

19 Dec 2016

Andrew Lin

(5)

Seminal paper for phase-transfer Heck-Mizoroki cross coupling

Reproducibility

Clarity

Versatility

A pinacle reaction of the synthesis required the cross coupling off a two highly heteroatom functionalised fragments, the use of traditional Heck conditions, such as palladium (II) acetate, triphenyl phosphine and triethylamine afforded poor yields and irreproducibility. Upon...

/paper/doi/10.1016/s0040-4039(00)73124-8	0.000000	0.000000
INIT	0.000208	0.000208
_initView	0.000931	0.001139
_initViewBasic	0.000166	0.001305
_initSiteModules	0.000210	0.001515
_initRouters	0.000145	0.001660
Sess +	0.001362	0.003022
Sess _	0.000228	0.003250
pre dispatch _	0.000243	0.003493
LC::doiAction START	0.000186	0.003679
LC::doiAction END to showListing	0.153839	0.157518
LC::showListing START	0.000004	0.157522
LC::showListing get reviews START	0.000016	0.157538
ES Review Search START	0.000591	0.158129
ES Review Search END	0.006403	0.164532
LC::showListing get reviews END	0.000928	0.165460
Done	0.026474	0.191934

Loading...

Tetraalkylammonium salts in heck-type reactions using an alkali metal hydrogen carbonate or an alkali metal acetate as the base

Tuyet Jeffery, Jean-Christophe Galland

Overall Rating

Review

Seminal paper for phase-transfer Heck-Mizoroki cross coupling

Recently Reviewed

Has Cited

Cited by

Sign In With