An efficient method for the preparation of N,N-disubstituted 1,2-diamines

  • 10.1016/s0040-4039(00)01501-x
  • Tetrahedron Letters
  • p 8431-8434, Volume 41, Issue 44,
  • journal-article


Good synthesis with comments for improvement

The article presents a synthetic methodology to prepare chiral N,N-disubstituted, 1,2-diamines, which can be convenient precursors to tridentate ligands.

Particularly, I used the synthetic route using cyclohexane-1,2-diamine (both racemic and enatiopure) to obtain a series,...