Design of a highly efficient catalyst for the oxaziridinium-mediated epoxidation of olefins by Oxone®

Luis Bohé , Majed Kammoun

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Paper Details

DOI 10.1016/j.tetlet.2003.11.040

Journal Tetrahedron Letters
Location p 747-751, Volume 45, Issue 4, 2004
Publication Type journal-article

Tags organic chemistry, biochemistry, drug discovery
Publisher Link Click Here

Review

07 Nov 2020

Anonymous

(0)

Post-Doc

Synthesis works, but yields can be difficult to achieve.

Logic / Design

Reproducibility

Impact

Transparency

Clarity

Versatility

As th electronegativity of the R-groups on the catalyst increases, yields tended to drop below reported values. While annoying, the purity of the finale compound was excellent.

On a more positive note, the route proposed in this publication can be easily applied to R-groups...

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Design of a highly efficient catalyst for the oxaziridinium-mediated epoxidation of olefins by Oxone®

Luis Bohé , Majed Kammoun

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Review

Synthesis works, but yields can be difficult to achieve.

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