1-Naphthyl-2-cyanoacetamide in heterocyclic synthesis: synthesis and evaluation of the antimicrobial activity of some new pyridine, pyrimidine, and naphtho[2,1-b]oxazine derivatives

  • 10.1007/s11164-014-1864-6
  • Research on Chemical Intermediates
  • p 7883-7897, Volume 41, Issue 10,
  • journal-article


Very well reproducible but greener solvents need to be used


This paper reports the reactivity of the methylene group of 1-naphthyl-2-cyanoacetamide 1 which was tested towards different reagents. These new compounds have been reported to be characterized by elemental analysis, IR, 1HNMR, 13C NMR, and mass spectral analysis....