| /paper/doi/10.1002/anie.200500227 | 0.000000 | 0.000000 |
| INIT | 0.005312 | 0.005312 |
| _initView | 0.010135 | 0.015447 |
| _initViewBasic | 0.001351 | 0.016798 |
| _initSiteModules | 0.001846 | 0.018644 |
| _initRouters | 0.002045 | 0.020689 |
| pre dispatch _ | 0.020294 | 0.040983 |
| LC::doiAction START | 0.000247 | 0.041230 |
| LC::doiAction END to showListing | 0.182433 | 0.223663 |
| LC::showListing START | 0.000007 | 0.223670 |
| LC::showListing get reviews START | 0.004762 | 0.228432 |
| ES Review Search START | 0.008555 | 0.236987 |
| ES Review Search END | 0.009432 | 0.246419 |
| LC::showListing get reviews END | 0.002464 | 0.248883 |
| Done | 0.047263 | 0.296146 |
Good reported synthesis with room for improvement
This article describes the structure optimization and initial mechanistic understanding of a simple thiourea catalyst for the enantioselective alkylation of indoles with nitroalkenes. The indole ring has proven to be a “privileged” structure in medicinal chemistry,...